Short answer
Get your serum folate tested, increase your intake of greens and legumes, and if you have a confirmed deficiency, talk to your doctor about taking supplements.
Vitamin B9 deficiency affecting hematopoiesis, nervous system and DNA synthesis
The mechanism in three steps, and where you can intervene.
Trigger
Lack of greens/legumes, alcoholism, gastrointestinal diseases (celiac disease, Crohn's disease), pregnancy
Mechanism
Impaired DNA synthesis → megaloblastic hematopoiesis + increased homocysteine
Symptom
Fatigue, pallor, mouth ulcers, cognitive impairment, neurological symptoms (if combined with B12 deficiency)
Answer 3 questions to see likely causes and a baseline lab list.
How long has this been going on?
Is there marked fatigue?
Is stress high?
Likely causes
What to check
We will show a preliminary result before registration
Create an action plan in one click with a checklist, reminders, and a timeline.
Get your serum folate tested, increase your intake of greens and legumes, and if you have a confirmed deficiency, talk to your doctor about taking supplements.
A baseline panel for the most common causes.
Primary marker of current vitamin B9 levels
Increased with folate/B12/B6 deficiency
Detection of macrocytic anemia (MCV > 100 fL)
Differential diagnosis (symptoms are similar)
How each marker relates to folate deficiency.
Deficiency occurs when there is a lack of fresh greens, legumes and liver in the diet. Those at risk include pregnant women, people with inflammatory bowel disease, and those taking methotrexate or anticonvulsants. Alcohol interferes with the absorption and accelerates the excretion of folate.
Serum folate is a key test (normal > 3 ng/ml). Homocysteine increases before clinical manifestations. CBC reveals megaloblastic anemia (high MCV). It's important to get B12 tested, as deficiencies often occur together. In Axioris you can download PDF analyzes and track the dynamics of indicators.
For folate levels <3 ng/mL, especially with symptoms of anemia or neurological impairment. Pregnant and planning pregnancy - even with borderline values. Urgently - when combined with high homocysteine (risk of thrombosis).
Taking folic acid without testing B12 (may worsen neurological symptoms of B12 deficiency). Ignoring elevated MCV in the CBC. Failure to take into account drug interactions (for example, taking phenytoin reduces folate levels).
«Axioris помог структурировать всё, что я сдала за год. Раньше результаты просто лежали в папке — теперь вижу динамику.»
«После второго ребёнка чувствовала себя разбитой. Анализы показали железо и ферритин в норме, но вот D₃ — 8. Решили.»
«Планировала тратить деньги на трихолога, но оказалось дефицит B12. Простой анализ, простая причина — нашла за 2 минуты.»
Основано на структурированном медицинском подходе, не на хаотичных советах из интернета.
Не заменяет очную консультацию и постановку диагноза врачом.
Срочные симптомы требуют немедленного обращения за медицинской помощью.
In case of severe deficiency, the doctor may prescribe therapeutic doses of 1-5 mg/day. To maintain levels, 400 mcg/day from supplements or foods (spinach, lentils, avocado) is sufficient.
Increases the risk of neural tube defects in the fetus. All pregnant women are recommended to take 400-800 mcg/day, starting from the planning stage.
No, the symptoms are non-specific. Fatigue and pallor can occur with iron deficiency (Fe), and neurological manifestations can occur with B12 deficiency. Laboratory diagnostics required.
You can upload PDF analyzes to Axioris: the system automatically recognizes the values of folate, MCV, homocysteine and builds graphs of changes. Reminds you of control tests.
Yes, consuming >300 mg caffeine/day (3 cups of coffee) reduces folate levels by 10-20%. If you have a deficiency, you should limit caffeine.
Сначала покажем результат, затем в 1 клик добавим план в Axioris для отслеживания.
Получить мой план