Lack of essential fatty acids, affecting brain function, heart function and inflammation
The mechanism in three steps, and where you can intervene.
Trigger
Lack of fatty fish, flaxseed, walnuts in the diet or impaired fat absorption
Mechanism
Reduced levels of EPA and DHA impair the fluidity of cell membranes and the synthesis of anti-inflammatory eicosanoids
Symptom
Dry skin, cognitive impairment, increased fatigue, prone to inflammation
Answer 3 questions to see likely causes and a baseline lab list.
How long has this been going on?
Is there marked fatigue?
Is stress high?
Likely causes
What to check
We will show a preliminary result before registration
Create an action plan in one click with a checklist, reminders, and a timeline.
Get tested for the omega-3 index, adjust your diet (fatty fish, flaxseed oil). If the deficiency is severe, your doctor may prescribe supplements. In Axioris, you can track the dynamics of indicators and receive reminders about repeat analyzes.
A baseline panel for the most common causes.
Shows the percentage of EPA and DHA from the total fatty acids in red blood cell membranes
Reflects the balance of pro- and anti-inflammatory fatty acids
Evaluates lipid metabolism, which may be disrupted by fatty acid imbalance
Marker of systemic inflammation, often elevated in omega-3 deficiency
How each marker relates to omega-3 deficiency.
The main reason is insufficient consumption of foods rich in EPA and DHA: fatty sea fish (salmon, mackerel, herring), seafood, flaxseed and camelina oil. Gastrointestinal diseases with impaired fat absorption (celiac disease, Crohn's disease), long-term low-fat diets and excess omega-6 in the diet (sunflower oil, fast food) also lead to deficiency.
The key analysis is the omega-3 index (normal >8%). Additionally, the omega-6/omega-3 ratio (optimally 2-4:1), total cholesterol and hs-CRP are checked as a marker of inflammation. You can download a PDF with the results of these analyzes into Axioris - the system will automatically recognize the values and build dynamics graphs, and also remind you of a control study 3-6 months after nutrition correction.
Consultation is needed if the omega-3 index is below 4%, severe cognitive impairment or cardiovascular risks. A doctor may prescribe high-dose supplements (1-2 g/day EPA+DHA) for confirmed deficiency. Pregnant women and people with bleeding disorders should take omega-3 supplements only under the supervision of a specialist.
1) Taking flaxseed oil instead of fish oil - ALA from plants does not convert well into DHA. 2) Ignoring the omega-6/omega-3 balance. 3) Refusal to monitor indicators when taking supplements. 4) Use of uncertified dietary supplements with oxidized fats. In Axioris, you can keep a diary of your supplement intake and track its effect on laboratory markers.
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Основано на структурированном медицинском подходе, не на хаотичных советах из интернета.
Не заменяет очную консультацию и постановку диагноза врачом.
Срочные симптомы требуют немедленного обращения за медицинской помощью.
With an index of 4-8% - 2-3 servings of oily fish per week or 500-1000 mg of EPA + DHA per day. If the index is <4%, therapeutic doses are 2-4 g/day under the supervision of a physician. The first changes in the analyzes appear after 2-3 months.
Plants contain only ALA, which in humans is converted to EPA/DHA with an efficiency of 5-10%. For vegans, algal oil with DHA and regular monitoring of the omega-3 index are recommended.
Look for GOED or IFOS certification, triglyceride form, EPA+DHA content ≥500 mg per capsule. Avoid supplements containing vitamin E as this may mask fat oxidation.
Dry skin and hair, frequent inflammation, memory loss, depression, increased fatigue. However, these symptoms are nonspecific, so laboratory diagnosis is important.
With normal indicators - once a year, when correcting a deficiency - after 3-6 months. In Axioris, you can set reminders for repeat analyzes and track dynamics on graphs.
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