Short answer
Monitor your weight dynamics in Axioris, check your thyroid hormones (TSH), glucose levels and inflammatory markers. If you lose >5% weight in 6 months, consult your physician.
Unexplained weight loss requires testing of key biomarkers
The mechanism in three steps, and where you can intervene.
Trigger
Hormonal disorders (hyperthyroidism, diabetes), chronic infections, oncological processes or psychogenic factors (stress, depression)
Mechanism
Accelerated metabolism in hyperthyroidism, loss of nutrients in malabsorption, catabolic processes in chronic inflammation
Symptom
>5% weight loss over 6 months without changes in diet/physical activity, often accompanied by weakness and fatigue
Answer 3 questions to see likely causes and a baseline lab list.
How long has this been going on?
Is there marked fatigue?
Is stress high?
Likely causes
What to check
We will show a preliminary result before registration
Create an action plan in one click with a checklist, reminders, and a timeline.
Monitor your weight dynamics in Axioris, check your thyroid hormones (TSH), glucose levels and inflammatory markers. If you lose >5% weight in 6 months, consult your physician.
A baseline panel for the most common causes.
Rules out hyperthyroidism as a cause of accelerated metabolism
Diagnosis of type 1 diabetes mellitus or latent autoimmune diabetes
Detection of anemia, inflammation or lymphoproliferative diseases
Marker of chronic inflammation or infectious process
Rule out hypercortisolism or adrenal insufficiency
How each marker relates to weight loss.
Pathological weight loss may be associated with endocrine disorders (hyperthyroidism, diabetes), chronic infections (tuberculosis, HIV), cancer or mental disorders (depression, anorexia). It is important to take into account the accompanying symptoms - increased sweating with thyrotoxicosis, thirst with diabetes, or prolonged low-grade fever with infections.
Start with basic screening: TSH, blood glucose, CBC and CRP. You can upload results to Axioris and track the dynamics of indicators. In case of deviations, the doctor may additionally prescribe hormonal panels, tumor markers or instrumental studies (ultrasound of the thyroid gland, CT scan of the chest).
Consultation with a physician is necessary if you lose more than 5% of body weight in 6 months, especially if this is accompanied by weakness, fever or other alarming symptoms. Urgent care is required if weight loss is combined with tachycardia, confusion, or signs of dehydration.
Dangerous misconceptions include attributing weight loss to “stress” without examination, ignoring weight loss in the elderly, or taking weight gain medications on your own without identifying the cause. In Axioris, use retest reminders to monitor progress.
«Axioris подсказал проверить кортизол в утреннее время. Результат удивил и объяснил, почему не могу утром нормально работать.»
«ТТГ оказался на границе. Без системной диагностики я бы ещё год занималась косметикой вместо причины.»
«Общий анализ крови я сдавала каждый год, но никогда не знала, что смотреть. Теперь вижу паттерны за 3 года.»
Основано на структурированном медицинском подходе, не на хаотичных советах из интернета.
Не заменяет очную консультацию и постановку диагноза врачом.
Срочные симптомы требуют немедленного обращения за медицинской помощью.
Yes, chronic stress increases cortisol levels, which can lead to decreased appetite and increased metabolism. However, you first need to rule out organic causes - check TSH, glucose and CRP.
A loss of more than 5% of body weight in 6 months or 10% in a year is considered clinically significant. It is especially alarming if weight loss occurs with normal/increased nutrition.
Basic hormonal screening includes TSH (thyroid), cortisol (adrenal), insulin, and glucose (carbohydrate metabolism). In Axioris, you can track the dynamics of these indicators in the “Biomarkers” section.
Axioris plots body weight changes, correlates them with laboratory values, and reminds you to repeat measurements. This helps to notice pathological dynamics in time.
Severe deficiency of B1, B12 or vitamin D can affect metabolism and appetite. Check these indicators if weight loss is accompanied by muscle weakness, neurological symptoms, or bone pain.
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