Short answer
Get tested for total and free testosterone, LH, prolactin. Rule out vitamin D and zinc deficiency. Contact an endocrinologist if there is a persistent decrease in indicators.
Male sex hormone deficiency affecting energy, libido and metabolism
The mechanism in three steps, and where you can intervene.
Trigger
Stress, obesity, zinc/D₃ deficiency, chronic inflammation, age-related decline after 30 years
Mechanism
Dysfunction of hypothalamic-pituitary regulation → decreased LH production → decreased testosterone synthesis in Leydig cells
Symptom
Fatigue, decreased muscle mass, depression, erectile dysfunction, decreased beard growth
Answer 3 questions to see likely causes and a baseline lab list.
How long has this been going on?
Is there marked fatigue?
Is stress high?
Likely causes
What to check
We will show a preliminary result before registration
Create an action plan in one click with a checklist, reminders, and a timeline.
Get tested for total and free testosterone, LH, prolactin. Rule out vitamin D and zinc deficiency. Contact an endocrinologist if there is a persistent decrease in indicators.
A baseline panel for the most common causes.
The main marker of androgenic status, taken in the morning on an empty stomach
Shows the functioning of the pituitary gland - the cause of the decrease (primary/secondary hypogonadism)
Affects the level of free testosterone - the biologically active fraction
Deficiency correlates with low testosterone, especially in obese men
Increased suppression of gonadotropin production
How each marker relates to low testosterone.
In addition to age-related decline, hypogonadism is caused by: metabolic syndrome (insulin resistance increases SHBG), chronic stress (cortisol competes for receptors), zinc deficiency (necessary for synthesis). Secondary causes are pituitary tumors, testicular injuries, and use of anabolic steroids.
Axioris conveniently monitors not only testosterone, but also related indicators: ferritin (anemia masks symptoms), TSH (hypothyroidism reduces LH), cortisol (for adrenal fatigue). The platform automatically builds dynamics graphs and reminds you of control analyses.
If two tests 2-4 weeks apart show total testosterone levels below 12 nmol/L (or free testosterone < 0.25 nmol/L) with symptoms. Urgently - for headaches + blurred vision (suspicion of prolactinoma).
1) Taking tests in the evening (the level drops by 30-40%). 2) Ignoring SHBG (if the level is high, total testosterone may be normal, but free testosterone may be low). 3) Self-medication with dietary supplements without correction of D₃ and zinc deficiency.
«Делала анализы хаотично, не понимала что искать. Теперь есть чёткий план и порядок — это само по себе снизило тревогу.»
«Витамин D был 12 — я даже не знала, что это влияет на усталость и иммунитет. После коррекции заметила разницу через 6 недель.»
«Мне 28, но гемоглобин падал каждую зиму. Axioris помог выстроить протокол поддержки — уже второй год без провалов.»
Основано на структурированном медицинском подходе, не на хаотичных советах из интернета.
Не заменяет очную консультацию и постановку диагноза врачом.
Срочные симптомы требуют немедленного обращения за медицинской помощью.
Yes, even one sleepless night reduces the level by 10-15%. Chronic lack of sleep disrupts the circadian rhythm of LH production.
Strength training 3 times a week, normalization of sleep (7-9 hours), correction of D₃/zinc deficiency, reduction of fat mass (aromatase in fat converts testosterone into estrogen).
No, modern research disproves this myth. Soy phytoestrogens do not affect hormone levels when consumed in moderation (up to 50 g/day).
Suppresses synthesis for 24 hours after 40 g of pure alcohol. Chronic use damages Leydig cells and increases SHBG.
Some testosterone is aromatized into estradiol. If you are obese or take anabolic steroids, this can lead to an imbalance: low testosterone + high estrogen = gynecomastia, mood swings.
Сначала покажем результат, затем в 1 клик добавим план в Axioris для отслеживания.
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